主要從事神經(jīng)系統(tǒng)感染與免疫相關(guān)周圍神經(jīng)疾病研究。現(xiàn)圍繞乙型腦炎病毒感染誘導(dǎo)宿主周圍神經(jīng)損傷，通過UPLC-HILIC-FLD、CUT&Tag、冷凍電鏡等開展靶抗原模擬物機制、Fc聚糖修飾及其與效應(yīng)細胞互作的分子調(diào)控和免疫復(fù)合物及其與FcγRs的結(jié)構(gòu)生物學(xué)研究。

以第一作者（含共同）在The New England Journal of Medicine, Emerging Microbes & Infection等期刊發(fā)表學(xué)術(shù)論文8篇，單篇最高影響因子91.245。中國學(xué)者2020年國際四大頂級醫(yī)學(xué)期刊論文學(xué)術(shù)影響力科學(xué)計分1268.16分。先后參與申報并完成國家自然科學(xué)基金面上項目和省級重點（重大）專項各2項。作為副主編撰寫《流行性乙型腦炎基礎(chǔ)與臨床》專著1部。獲省級自然科學(xué)優(yōu)秀學(xué)術(shù)論文一等獎1項（排名第1），省級科技進步二等獎1項（排名第3），參與申報國家發(fā)明專利4項。

1. Guowei Wang*, Haining Li, Xiaojun Yang, Tao Guo, Libin Wang, Zhijun Zhao, Haifeng Sun, Xiaolin Hou, Xiangchun Ding, Chunyang Dou, Qiaoli Ma, Xiao Yang, Yanbo Wang, Zhao Wang, Luxuan Wang, Jixiang Liu, Zhenhai Wang, Huanyu Wang, Peng Xie. Guillain-Barré Syndrome Associated with JEV Infection. N Engl J Med. 2020 Sep 17;383(12):1188-1190. (IF: 91.245) 

2. Guowei Wang*, Lianmei Zhong*, Manxia Wang*, Juan Zhou*, Shuting Liu, Wang Miao, Leilei Li, Yonghong Liu, Shougang Guo, Haining Li, Xiaoming Wang, Liuqing Xie, Min Xie, Shihong Fu, Tingting Xuan, Fan Li, Tingting Yang, Lufei Shao, Mingfang Shi, Xiaocong Li, Xiaoling Li, Li Gao, Shaopeng Zhai, Jia Ding, Tianhong Wang, Dayong Liu, Guosheng Ma, Jiang Wu, Dongjun Wan, Junlin Guo, Xinbo Zhang, Jinxia Wu, Yinxu Wang, Ansong Jin, Lei Ma, Huan Yang, Xuexian He, Xiaona Ma, Huijuan Liu, Boya Ma, Ningai Yang, Xiaolin Hou, Ting Xu, Cheng-Feng Qin, Huanyu Wang, Peng Xie, Zhenhai Wang. Peripheral nerve injury associated with JEV infection in high endemic regions, 2016-2020: a multicenter retrospective study in China. Emerg Microbes Infect. 2024 Dec;13(1):2337677. (IF: 13.2) 

3. Fan Li*, Yun Feng*, Guowei Wang*, Weijia Zhang, Shihong Fu, Zuosu Wang, Qikai Yin, Kai Nie, Juying Yan, Xuan Deng, Ying He, Liang Liang, Songtao Xu, Zhenhai Wang, Guodong Liang, Huanyu Wang. Tracing the spatiotemporal phylodynamics of Japanese encephalitis virus genotype I throughout Asia and the western Pacific. PLoS Negl Trop Dis. 2023 Apr 13;17(4):e0011192. (IF: 4.8) 

4. Xiaoli Wang*, Guowei Wang*, Huan Yang, Shihong Fu, Ying He, Fan Li, Huanyu Wang, Zhenhai Wang. A mouse model of peripheral nerve injury induced by Japanese encephalitis virus. PLoS Negl Trop Dis. 2022 Nov 28;16(11):e0010961. (IF: 4.4) 

5. Zhao Wang*, Guowei Wang*, Yanbai Wang, Qiang Liu, Haining Li, Peng Xie, Zhenhai Wang. Omp31 of Brucella Inhibits NF-κB p65 Signaling Pathway by Inducing Autophagy in BV-2 Microglia. Neurochem Res. 2021 Dec;46(12):3264-3272. (IF: 4.0) 

6. Luxuan Wang*, Guowei Wang*, Yangyang Duan, Feng Wang, Shaoqing Lin, Fengting Zhang, Hui Li, Andy Li, Haining Li. A Comparative Study of the Diagnostic Potential of Plasma and Erythrocytic α-Synuclein in Parkinson's Disease. Neurodegener Dis. 2019;19(5-6):204-210. (IF: 2.4) 

7. Huan Yang, Xiaoli Wang, Zhao Wang, Guowei Wang, Shihong Fu, Fan Li, Liping Yang, Yanping Yuan, Kaichun Shen, Huanyu Wang, Zhenhai Wang. Peripheral Nerve Injury Induced by Japanese Encephalitis Virus in C57BL/6 Mouse. J Virol. 2023 May 31;97(5):e0165822. (IF: 6.5)